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Correspondence
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Volume 341:290-291 July 22, 1999 Number 4
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Oligoarthritis Mediated by Tumor-Specific T Lymphocytes in Renal-Cell Carcinoma

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To the Editor: There are few reports describing the pathophysiologic features of paraneoplastic arthritis in patients with solid tumors.1,2,3 We report on a patient with oligoarthritis as the initial manifestation of renal-cell carcinoma.

A 60-year-old man presented with recurrent pain and swelling of the left knee and right elbow, which he had had for two years. Four months earlier, a Baker's cyst of the left knee had been removed, and histologic examination revealed moderate chronic synovitis (Figure 1A). Physical examination revealed arthritis of the left knee and right elbow, but the findings were otherwise normal. The patient's erythrocyte . . . [Full Text of this Article]

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