FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 341:453-455 August 5, 1999 Number 6 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Kulke, M. H. PubMed Citation

To the Editor: In the article by Kulke and Mayer (March 18 issue),¹ it is stated with respect to the biochemical diagnosis of carcinoid tumors that measurement of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) in a 24-hour urine collection may be useful in confirming the diagnosis. We would like to draw attention to the measurement of other biogenic amines — such as serotonin, catecholamines, and histamine and its metabolites — in the platelets, plasma, and urine of patients with carcinoid tumors.

By using high-performance liquid chromatography and gas chromatography–mass spectrometry, we have characterized carcinoid tumors in more than 100 patients. . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Mulder, E. J., Oosterloo-Duinkerken, A., Anderson, G. M., De Vries, E. G.E., Minderaa, R. B., Kema, I. P. (2005). Automated On-Line Solid-Phase Extraction Coupled with HPLC for Measurement of 5-Hydroxyindole-3-acetic Acid in Urine. Clin. Chem. 51: 1698-1703 [Abstract] [Full Text]