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Volume 341:459-460 August 5, 1999 Number 6
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Contagion and Confinement: Controlling tuberculosis along the Skid Road

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By Barron H. Lerner. 243 pp. Baltimore, Johns Hopkins University Press, 1998. $42.50. ISBN 0-8018-5898-4.

In the early 20th century, tuberculosis was the leading cause of death. Tens of thousands of people wasted away as a result of the white plague. Sanatoriums offered fresh air, bed rest, regular meals, and gradual exercise, but with the discovery of streptomycin in 1944 a new era of effective treatment for tuberculosis began. Aminosalicylic acid was added in 1949 and isoniazid in 1952. Early preparations of isoniazid had stimulant effects. Lerner notes that "pictures of formerly gravely ill patients dancing in the halls" contributed to isoniazid's reputation as a wonder drug.

Tuberculosis is a chronic disease with important medical, . . . [Full Text of this Article]




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