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Previous Volume 341:531-534 August 12, 1999 Number 7 Next

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The Declaration of Helsinki requires revision because it is defective in two important respects. First, it relies on a distinction between therapeutic and nontherapeutic research; all documents that rely on this spurious distinction contain errors not intended by their authors.¹ Second, it includes several provisions that are seriously out of touch with contemporary ethical thinking. As a consequence, many researchers routinely violate its requirements. Such routine violations and their associated attitudes rob the declaration of its credibility.

Therapeutic and Nontherapeutic Research

The nature of the errors that arise from a reliance on the distinction between therapeutic and nontherapeutic research is made clear by placing . . . [Full Text of this Article]

Control Groups in Randomized Clinical Trials

References

Related Letters:

Should the Declaration of Helsinki Be Revised?
Morens D. M., Kopp V. J., Senn S., Macpherson C. C., O'Ryan M., Misbin R. I., Levine R. J.
Extract | Full Text  
N Engl J Med 1999; 341:1851-1853, Dec 9, 1999. Correspondence

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