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Editorial
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Volume 342:52-53 January 6, 2000 Number 1
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Noninvasive Testing for Fetal Anemia

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 by Mari, G.
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Despite the introduction of anti-D immune globulin (Rh immunoglobulin) for the prevention of anti-D red-cell alloimmunization, hemolytic disease of the newborn continues to occur because of the lack or failure of prophylaxis or because of maternal alloimmunization against other red-cell antigens for which prophylaxis is not available. The central tenet in the management of pregnancies complicated by red-cell alloimmunization is the detection of fetal anemia and intervention, by either intrauterine transfusion or delivery, before fetal death. Fetal anemia is usually diagnosed in a stepwise fashion, starting with less sensitive but less invasive screening methods (obtaining the reproductive history and measuring . . . [Full Text of this Article]

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