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Volume 342:820-821 March 16, 2000 Number 11
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The Economic Implications of HLA Matching in Cadaveric Renal Transplantation

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 by Schnitzler, M. A.
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To the Editor: In their study of the economic implications of HLA matching in cadaveric renal transplantation (Nov. 4 issue),1 Schnitzler and colleagues probably overstate the economic benefits of a strictly local organ-allocation system. They overestimate the fraction of local recipients who would receive a locally procured HLA-matched cadaveric kidney. The use of HLA-matched kidneys significantly enhances graft survival and thereby lowers post-transplantation costs. In our study,2 on which the authors based their fractions, we assumed that whereas HLA-mismatched kidneys were allocated locally, HLA-matched kidneys were shared nationally. In regions with 750 waiting patients (the local-pool size used by the . . . [Full Text of this Article]

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