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Correction to Mayeux and Sano, N Engl J Med 341(22):1670-1679 November 25, 1999.

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Volume 342:821-822 March 16, 2000 Number 11
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Treatment of Alzheimer's Disease

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 by Mayeux, R.
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 by Mayeux, R.
To the Editor: In their article on the treatment of Alzheimer's disease (Nov. 25 issue),1 Mayeux and Sano failed to mention AIT-082 (leteprinim potassium, Neotrofin), galantamine, or lazabemide but included such dubious treatments as Gingko biloba and acetyl-l-carnitine. Furthermore, the inclusion of metrifonate, rivastigmine, and eptastigmine, all of which are cholinesterase inhibitors not yet available in the United States, and the omission of huperzine A were puzzling indeed. Huperzine A, a Chinese herb, is a reversible cholinesterase inhibitor like tacrine and donepezil,2 but it may be more effective than either of those drugs. In fact, it may bind to cholinesterase . . . [Full Text of this Article]

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