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Correspondence
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Volume 342:976-977 March 30, 2000 Number 13
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Treatment of Primary Hyperparathyroidism

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 by Utiger, R. D.
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To the Editor: We take issue with some of the recommendations made by Utiger in his editorial on the treatment of primary hyperparathyroidism (Oct. 21 issue).1 Measurement of serum calcium was advocated, with no mention of correction for abnormal serum albumin concentrations or measurement of serum ionized calcium. We and others have found that measurements of serum ionized calcium are superior to measurements of serum total calcium or albumin-corrected calcium in the diagnosis of primary hyperparathyroidism.2,3 In our study of 60 patients with pathologically confirmed primary hyperparathyroidism, 22 percent of the patients had corrected serum total calcium concentrations within the . . . [Full Text of this Article]

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