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Previous Volume 342:1119-1120 April 13, 2000 Number 15 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In this issue of the Journal, Stadtmauer et al. present the results of a clinical trial in which conventional-dose chemotherapy was compared with high-dose chemotherapy plus autologous bone marrow transplantation (hematopoietic stem-cell rescue) in patients with metastatic breast cancer.¹ In this trial, 553 women with previously untreated metastatic or locally recurrent breast cancer were initially treated with conventional multidrug chemotherapy; patients who had a response, according to predefined objective criteria, were then randomly assigned to receive either maintenance chemotherapy at standard doses or high-dose chemotherapy plus an autologous bone marrow transplant. In this randomization phase, a total of 199 women . . . [Full Text of this Article]

References

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• Gratwohl, A., Baldomero, H., Schwendener, A., Gratwohl, M., Apperley, J., Niederwieser, D., Frauendorfer, K., for the Joint Accreditation Committee of the Inter, (2007). Predictability of hematopoietic stem cell transplantation rates. haematol 92: 1679-1686 [Abstract] [Full Text]  
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• Shenkier, T., Weir, L., Levine, M., Olivotto, I., Whelan, T., Reyno, L. (2004). Clinical practice guidelines for the care and treatment of breast cancer: 15. Treatment for women with stage III or locally advanced breast cancer. CMAJ 170: 983-994 [Abstract] [Full Text]  
• Welch, H G., Mogielnicki, J. (2002). Presumed benefit: lessons from the American experience with marrow transplantation for breast cancer. BMJ 324: 1088-1092 [Full Text]  
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