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Previous Volume 342:1216-1218 April 20, 2000 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: My colleagues and I began evaluating children with autism and gastrointestinal problems in 1997 and reported our findings initially in 1998.¹ The main secretin-related observation was a significant increase in the volume of pancreaticobiliary fluid after intravenous injection of secretin during endoscopy in 75 percent of the 36 autistic children we studied.² Most of the children had gastrointestinal changes after a single dose of secretin. The majority of these patients had gradual improvements in social and behavioral skills after repeated injections. Of course, to prove scientifically that secretin is beneficial in the treatment of autism, randomized, double-blind, . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Levy, S E, Souders, M C, Wray, J, Jawad, A F, Gallagher, P R, Coplan, J, Belchic, J K, Gerdes, M, Mitchell, R, Mulberg, A E (2003). Children with autistic spectrum disorders. I: Comparison of placebo and single dose of human synthetic secretin. Arch. Dis. Child. 88: 731-736 [Abstract] [Full Text]  
• Levy, S. E (2002). Repeated doses of porcine secretin did not improve symptoms, language, or cognitive functioning in children with autism or autism spectrum disorder. Evid. Based Ment. Health 5: 22-22 [Full Text]