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Previous Volume 342:1529-1531 May 18, 2000 Number 20 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Type 1 diabetes mellitus is an organ-specific T-cell–mediated autoimmune disease characterized by cellular infiltration of pancreatic islets (insulitis) and destruction of insulin-producing beta cells. Congenital diabetes is extremely rare, and very little is known about its pathogenesis.¹

We describe a neonate in whom hyperglycemia, glycosuria, and moderate acidosis developed 12 hours after birth. He was born at 34 weeks of gestation and was small for gestational age (1600 g). His mother was healthy and had had an uncomplicated pregnancy. Congenital diabetes was confirmed by the finding of low serum C-peptide and insulin concentrations. Intravenous treatment with insulin . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Stanley, H. M., Norris, J. M., Barriga, K., Hoffman, M., Yu, L., Miao, D., Erlich, H. A., Eisenbarth, G. S., Rewers, M. (2004). Is Presence of Islet Autoantibodies at Birth Associated With Development of Persistent Islet Autoimmunity?: The Diabetes Autoimmunity Study in the Young (DAISY). Diabetes Care 27: 497-502 [Abstract] [Full Text]  
• Wildin, R S, Smyk-Pearson, S, Filipovich, A H (2002). Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome. J. Med. Genet. 39: 537-545 [Abstract] [Full Text]