FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 342:1612-1613 May 25, 2000 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Miller, S. T. PubMed Citation

To the Editor: In a well-designed and informative study, Miller and colleagues (Jan. 13 issue)¹ demonstrated that among children with sickle cell disease who were younger than two years of age, dactylitis, severe anemia, or an elevated leukocyte count predicted an adverse outcome later in childhood. An adverse outcome was defined as any one of the following: frequent pain, recurrent acute chest syndrome, stroke, or death. Using the three predictors, they developed a prognostic model to identify children who might benefit from high-risk therapies.

We believe the model would be more clinically useful if only death and stroke were included . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Quinn, C. T., Rogers, Z. R., Buchanan, G. R. (2004). Survival of children with sickle cell disease. Blood 103: 4023-4027 [Abstract] [Full Text]  
• Claster, S., Vichinsky, E. P (2003). Managing sickle cell disease. BMJ 327: 1151-1155 [Full Text]