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Volume 342:1617-1618 May 25, 2000 Number 21
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Neurobiology of Mental Illness

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Edited by Dennis S. Charney, Eric J. Nestler, and Benjamin S. Bunney. 958 pp., illustrated. New York, Oxford University Press, 1999. $150. ISBN 0-19-511265-2.

I recently picked up a copy of the two-volume, multiauthored American Handbook of Psychiatry (Silvano Arieti, ed. New York, Basic Books), published in 1959. Neurobiology was represented only in a few sections, notably in one entitled Organic Conditions, which included discussions of neurosyphilis, dementia, epilepsy, behavioral disorders after brain lesions, Huntington's disease, and mental retardation. The so-called functional disorders (schizophrenia, affective disorders, and anxiety disorders) were examined in great detail, but there was little regarding abnormalities of the brain. Many varieties of psychotherapy were referred to as primary methods of treatment. The list of "physical therapies" included insulin shock, convulsive . . . [Full Text of this Article]




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