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Original Article
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Volume 342:1638-1643 June 1, 2000 Number 22
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Transfusions of Polymerized Bovine Hemoglobin in a Patient with Severe Autoimmune Hemolytic Anemia
John Mullon, M.D., George Giacoppe, M.D., Cynthia Clagett, M.D., David McCune, M.D., and Thomas Dillard, M.D.

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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 by Klein, H. G.
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Hemoglobin solutions have several potential advantages as substitutes for erythrocytes for transfusion. Hemoglobin solutions have a prolonged shelf life, are associated with a lower risk of transfusion reactions, and provide faster uptake of oxygen.1 Hemoglobin-based oxygen carriers (HBOC) have been studied primarily in patients with hemorrhage, but the absence of cell-surface antigens in these solutions suggests that they may have a role in the treatment of autoimmune hemolytic anemias. We report the use of a polymerized bovine hemoglobin, HBOC-201 (Hemopure, Biopure, Cambridge, Mass.), in a woman with severe autoimmune hemolytic anemia.

Case Report

A 21-year-old woman with a petechial rash and gingival . . . [Full Text of this Article]

Methods

Results

Relief of Ischemia

Hemodynamic Response

Clinical Outcome

Discussion


Source Information

From the Department of Medicine, Madigan Army Medical Center, Tacoma, Wash. (J.M., G.G., C.C., D.M., T.D.); and the Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Md. (T.D.).

Address reprint requests to Dr. Mullon at the Department of Medicine, Madigan Army Medical Center, Tacoma, WA 98431, or at jkmullon@worldnet.att.net.

References


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Extract | Full Text  
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