Hemoglobin solutions have several potential advantages as substitutesfor erythrocytes for transfusion. Hemoglobin solutions havea prolonged shelf life, are associated with a lower risk oftransfusion reactions, and provide faster uptake of oxygen.1Hemoglobin-based oxygen carriers (HBOC) have been studied primarilyin patients with hemorrhage, but the absence of cell-surfaceantigens in these solutions suggests that they may have a rolein the treatment of autoimmune hemolytic anemias. We reportthe use of a polymerized bovine hemoglobin, HBOC-201 (Hemopure,Biopure, Cambridge, Mass.), in a woman with severe autoimmunehemolytic anemia.
From the Department of Medicine, Madigan Army Medical Center, Tacoma, Wash. (J.M., G.G., C.C., D.M., T.D.); and the Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Md. (T.D.).
Address reprint requests to Dr. Mullon at the Department of Medicine, Madigan Army Medical Center, Tacoma, WA 98431, or at jkmullon@worldnet.att.net.
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