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Figure 1. An eight-year-old girl had a four-month history of painful mouth lesions, resulting in decreased oral intake and weight loss, and a one-year history of intermittent abdominal pain and irregular bowel movements. On examination, she had cheilitis, redness and swelling of the gingiva, and oral ulcerations (Panels A and B), as well as tenderness of the right lower quadrant and a perianal fissure. Colonoscopy with multiple biopsies revealed findings consistent with the presence of Crohn's disease. Five weeks after the initiation of treatment with 40 mg of oral prednisone daily (2 mg per kilogram of body weight), the . . . [Full Text of this Article] |
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