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Medical, social, and public health advances have dramatically increased the average age of the human population in many parts of the world. One consequence of these advances is the increasing proportion of elderly persons in Western societies. Not only are the elderly more numerous as a segment of society, but also more of the persons who are living longer are enjoying relatively good health. These points have important implications for public policy, but they also create new challenges with respect to understanding the biology of advanced age. The natural attributes of aging, such as menopause and declining bone mass, which
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