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Volume 342:1830-1833 June 15, 2000 Number 24
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Rules for Research on Human Genetic Variation — Lessons from Iceland

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Research on genetic variation aims to understand how genes function and requires the comparison of DNA samples from groups of individuals to identify variations that might have importance for health or disease.1 This work is easier if the samples are linked to accurate medical records and genealogic information. Iceland has medical records for all its citizens going back to World War I and detailed genealogic information going back even further. Because Iceland's small population (270,000) has long been isolated and homogeneous, it is thought by many to be an ideal place to search for disease-related genes. Journalists have cavalierly labeled . . . [Full Text of this Article]

Community Consultation and Benefit

Individual Consent

Generic Genetic Consent and Withdrawal of Consent

DNA and Medical Records in the Future

References


Related Letters:

The Icelandic Healthcare Database
Winickoff D., Arnason E., Gulcher J. R., Stefansson K.
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N Engl J Med 2000; 343:1734-1735, Dec 7, 2000. Correspondence

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