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Correspondence
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Volume 342:1838-1839 June 15, 2000 Number 24
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Prevalence of Gynecologic Cancer in Women Exposed to Diethylstilbestrol in Utero

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To the Editor: Exposure to diethylstilbestrol (DES) in utero is related to an increased risk of clear-cell adenocarcinoma of the vagina and cervix at a young age.1 However, the long-term risk of cancer in the daughters of women given DES during pregnancy (DES daughters) is still unknown. To date, only one study has examined the risk of cancer in adult DES daughters, and no increased risks were found in that study, except for an increased risk of clear-cell adenocarcinoma of the vagina and cervix.2

We analyzed data from a questionnaire mailed to 13,350 DES daughters registered at the Netherlands DES . . . [Full Text of this Article]

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