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Figure 1. A previously healthy 16-year-old girl presented with a three-day history of progressive pain on the left side of her chest. A chest x-ray film showed a large left-sided pneumothorax with bilateral cystic radiolucencies, and a chest tube was inserted. A high-resolution computed tomographic scan demonstrated the pneumothorax and multiple thin-walled cysts throughout the lungs, especially in the upper lobes (Panel A). Diagnostic thoracoscopy, with the endoscope inserted in the space around the chest tube, showed multiple subpleural cysts (Panel B). A thoracoscopic wedge-biopsy specimen was obtained. Histologic evaluation demonstrated nodular aggregates of Langerhans' cells (arrows in Panel . . . [Full Text of this Article]
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Pulmonary Langerhans'-Cell Histiocytosis
Brown R. E., Arico M., Nichols K. E., Danesino C., O'Regan A. W., Brophy M. T., Miller W. T., Vassallo R., Ryu J. H., Limper A. H.
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N Engl J Med 2000;
343:1654-1656, Nov 30, 2000.
Correspondence
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[Abstract][Full Text]
Brown, R. E., Arico, M., Nichols, K. E., Danesino, C., O'Regan, A. W., Brophy, M. T., Miller, W. T., Vassallo, R., Ryu, J. H., Limper, A. H.
(2000). Pulmonary Langerhans'-Cell Histiocytosis. NEJM
343: 1654-1656
[Full Text]
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