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Previous Volume 342:2005-2006 June 29, 2000 Number 26 Next

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By Arnold M. Katz. 397 pp., illustrated. Philadelphia, Lippincott Williams & Wilkins, 2000. $65. ISBN 0-7817-1549-0.

Heart failure is one of the most frequent reasons patients are admitted to the hospital. The incidence of heart failure is rising sharply in countries throughout the world, including developing countries. Despite advances in its treatment, heart failure still has a poor prognosis.

The treatment of heart failure has shifted over the years from the administration of diuretic agents to the provision of positive inotropic support to the inhibition of the neurohumoral axis. The changes in treatment reflect changes in concepts of the pathophysiology of heart failure. One attractive idea is the crucial role of cardiac hypertrophy as an adaptive . . . [Full Text of this Article]

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