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Volume 343:66-68 July 6, 2000 Number 1
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Noninvasive Diagnosis of Fetal Anemia by Doppler Ultrasonography

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 by Mari, G.
To the Editor: The results of the analysis of Doppler ultrasonography for the diagnosis of fetal anemia caused by maternal red-cell alloimmunization reported by Mari and colleagues (Jan. 6 issue)1 are promising, but a note of caution must be sounded. The investigators determined the accuracy of ultrasonography in the same group of fetuses in which they determined the threshold values for the peak systolic velocity in the middle cerebral artery at various gestational ages (>1.5 multiples of the median). The potential danger in this approach is obvious: since only 35 fetuses had moderate or severe anemia and only 23 of . . . [Full Text of this Article]

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