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Correspondence
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Volume 343:70-71 July 6, 2000 Number 1
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Case 3-2000

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 by DiSalvo, T. G.
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To the Editor: The January 27 Case Record (Case 3-2000)1 concerned a patient who had systemic amyloidosis, AL type, with restrictive cardiomyopathy and multiple organ involvement. I wish to draw attention to amyloidosis of the adrenal glands, which Dr. DiSalvo mentioned briefly.

Secondary amyloidosis (AA type) is a rare cause of primary adrenal insufficiency (accounting for 1.73 percent of cases in one series),2 since extensive accumulation of amyloid and destruction of the adrenal cortex are necessary to produce clinical symptoms. Secondary adrenal insufficiency and hypopituitarism are even more rare, occurring if there is destruction of the pituitary gland.3 Primary amyloidosis . . . [Full Text of this Article]

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