To the Editor: The Acute Respiratory Distress Syndrome Networkinvestigators (May 4 issue)1 deserve commendation for theirimportant study. Because of its importance and despite the clarityof the results, several points should be made.
First, this study was not simply a comparison of high and lowtidal volumes, but rather a comparison of two distinct and highlyspecific strategies of ventilatory management, with differencesin tidal volume and airway pressure. Use of positive end-expiratorypressure was specified by the protocol, and on days 1 and 3of the study, the group treated with lower tidal volumes hadsignificantly higher . . . [Full Text of this Article]
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