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Correspondence
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Volume 343:812-814 September 14, 2000 Number 11
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Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury

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 by The Acute Respiratory Distress Syndrome Network
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To the Editor: The Acute Respiratory Distress Syndrome Network investigators (May 4 issue)1 deserve commendation for their important study. Because of its importance and despite the clarity of the results, several points should be made.

First, this study was not simply a comparison of high and low tidal volumes, but rather a comparison of two distinct and highly specific strategies of ventilatory management, with differences in tidal volume and airway pressure. Use of positive end-expiratory pressure was specified by the protocol, and on days 1 and 3 of the study, the group treated with lower tidal volumes had significantly higher . . . [Full Text of this Article]

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