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Volume 343:814-815 September 14, 2000 Number 11
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Daily Interruption of Sedative Infusions in Critically Ill Patients

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 by Heffner, J. E.
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 by Kress, J. P.
To the Editor: Kress et al. (May 18 issue)1 report that daily interruption of sedative infusions in patients requiring mechanical ventilation resulted in a decreased duration of mechanical ventilation and a decreased length of stay in the intensive care unit. They note that patients in the intervention group were awake 85.5 percent of the days during which they were receiving an infusion, as compared with 9.0 percent of days for the patients in the control group, but did not comment on this important finding. Presumably, patients in the intervention group were weaned from mechanical ventilation and extubated sooner because they . . . [Full Text of this Article]

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