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Correspondence
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Volume 343:817-818 September 14, 2000 Number 11
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Hypernatremia

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 by Adrogué, H. J.
To the Editor: In the review article on hypernatremia by Adrogué and Madias (May 18 issue),1 we wonder whether the patient described as having a pure water loss does not in fact have a sodium gain as well. Our reasoning is that if a 20 percent increase in the plasma sodium concentration is due to a pure water deficit, then there should be a corresponding 20 percent reduction in the total body water distributed equally among the intracellular-fluid and the extracellular-fluid compartments. A decline in the extracellular fluid of this degree should have been clinically apparent, identifiable at least by . . . [Full Text of this Article]

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