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Correspondence
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Volume 343:884-885 September 21, 2000 Number 12
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Ropinirole as Compared with Levodopa in Parkinson's Disease

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 by Rascol, O.
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To the Editor: Rascol et al. (May 18 issue)1 summarize the results of their study by stating that Parkinson's disease is best managed with ropinirole alone as the initial treatment, with levodopa used as a supplemental, second step if necessary. This recommendation is based on their finding that the risk of dyskinesias (medication-induced chorea) is lower with ropinirole.

If a reduced risk of dyskinesia is to be the basis for making a recommendation with such broad implications, then the magnitude of the problem must warrant this concern. We reviewed the medical records of 350 randomly chosen patients with Parkinson's disease . . . [Full Text of this Article]

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