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Volume 343:893 September 21, 2000 Number 12
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Challenges in Colorectal Cancer

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Edited by John H. Scholefield. 230 pp., illustrated. Malden, Mass., Blackwell Science, 2000. $139.95. ISBN 0-632-05116-7.

Colorectal cancer presents some of the most challenging problems for basic scientists, clinical investigators, and practitioners. It will be important to facilitate an ongoing exchange among these three groups if we are to transform many small steps into a major advance in the treatment of colorectal cancer. Surgery remains the center of attention, for two reasons. First, in any high-risk case, the surgeon must coordinate the various treatment options (e.g., preoperative, intraoperative, and postoperative adjuvant treatment); second, the surgeon determines the prognosis, since inadequate surgical technique can influence a patient's outcome more than can the stage of the disease. But . . . [Full Text of this Article]




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