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Previous Volume 343:969-970 September 28, 2000 Number 13 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Vascular complications cause serious morbidity in patients with diabetes mellitus. Two such complications are diabetic nephropathy and restenosis after percutaneous transluminal coronary angioplasty. There is currently scant evidence of a genetic marker that predicts which patients will have these complications.

Oxidative stress plays an important part in the development of diabetic vascular complications.¹ Haptoglobin is a hemoglobin-binding protein that has a major role in providing protection against heme-driven oxidative stress.² There are two common alleles for haptoglobin (1 and 2), and the three phenotypes, haptoglobin 1/1, haptoglobin 2/1, and haptoglobin 2/2, differ in their ability to function . . . [Full Text of this Article]

References

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• Nakhoul, F., Abassi, Z., Morgan, M., Sussan, S., Mirsky, N. (2006). Inhibition of Diabetic Nephropathy in Rats by an Oral Antidiabetic Material Extracted from Yeast. J. Am. Soc. Nephrol. 17: S127-S131 [Abstract] [Full Text]  
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