FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 343:1047-1048 October 5, 2000 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

To the Editor: Critically ill patients who are receiving enteral feeding are susceptible to pulmonary aspiration of gastric contents. Measures to enhance the early detection of aspiration include the tinting of feedings with the food dye FD&C blue no. 1.¹ During sepsis, gastrointestinal permeability increases because of enterocyte death and loss of barrier function at intercellular gaps. Thus, substances that are otherwise nonabsorbable may be absorbed during sepsis.² We report two deaths associated with the systemic absorption of blue dye no. 1 from enteral feedings; in both cases, the absorption was heralded by the appearance of blue or green skin . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Mehta, N. M. (2009). Approach to Enteral Feeding in the PICU. Nutr Clin Pract 24: 377-387 [Abstract] [Full Text]  
• Baskin, W. N. (2006). Acute Complications Associated with Bedside Placement of Feeding Tubes. Nutr Clin Pract 21: 40-55 [Abstract] [Full Text]  
• American Society for Parenteral and Enteral Nutrit, , and Task Force on Standards for Specialized Nutrit, , Jane Balint, , Catherine Crill, , Kimberly Klotz, (2005). Standards for Specialized Nutrition Support: Hospitalized Pediatric Patients. Nutr Clin Pract 20: 103-116 [Full Text]  
• Parker, C. M., Heyland, D. K. (2004). Aspiration and the Risk of Ventilator-Associated Pneumonia. Nutr Clin Pract 19: 597-609 [Abstract] [Full Text]  
• St. John, R. E. (2004). Airway Management. Crit Care Nurse 24: 93-97 [Full Text]  
• Gaur, S, Sorg, T, Shukla, V (2003). Systemic absorption of FD&C blue dye associated with patient mortality. Postgrad. Med. J. 79: 602-603 [Abstract] [Full Text]  
• Maloney, J. P., Ryan, T. A. (2002). Detection of Aspiration in Enterally Fed Patients: A Requiem for Bedside Monitors of Aspiration. JPEN J Parenter Enteral Nutr 26: S34-S42 [Abstract]  
• DiSario, J. A. (2002). Future Considerations in Aspiration Pneumonia in the Critically Ill Patient: What Is Not Known, Areas for Future Research, and Experimental Methods. JPEN J Parenter Enteral Nutr 26: S75-S79 [Abstract]  
• Maloney, J., Metheny, N. (2002). Controversy in using blue dye in enteral tube feeding as a method of detecting pulmonary aspiration.. Crit Care Nurse 22: 84-85 [Full Text]  
• Metheny, N. A., Dahms, T. E., Stewart, B. J., Stone, K. S., Edwards, S. J., Defer, J. E., Clouse, R. E. (2002). Efficacy of Dye-Stained Enteral Formula in Detecting Pulmonary Aspiration*. Chest 122: 276-281 [Abstract] [Full Text]  
• Metheny, N. A., Chang, Y.-H., Ye, J. S., Edwards, S. J., Defer, J., Dahms, T. E., Stewart, B. J., Stone, K. S., Clouse, R. E. (2002). Pepsin as a Marker for Pulmonary Aspiration. Am J Crit Care 11: 150-154 [Abstract] [Full Text]  
• Clay, A. S., Behnia, M., Brown, K. K. (2001). Mitochondrial Disease : A Pulmonary and Critical-Care Medicine Perspective. Chest 120: 634-648 [Abstract] [Full Text]