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Previous Volume 343:1163-1166 October 19, 2000 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Histoplasmosis may occur either after primary infection or after reactivation of latent infection, and its incidence among immunocompromised persons, including recipients of organ transplants, is increasing.^1,2,3 A variety of infectious agents are known to be transmissible by organ transplantation,⁴ but there has been no definitive evidence of transmission of Histoplasma capsulatum by this route. In the few previous reports of possible cases of such transmission, neither reactivation of latent infection nor primary infection from an environmental source was definitively ruled out.^5,6,7,8

Recently, molecular typing of H. capsulatum has been shown to be useful in distinguishing relapse from reinfection among patients . . . [Full Text of this Article]

Case Reports

Recipient 1

Recipient 2

Recipient 3

Donor

Methods

Results

Discussion

Source Information

From the Departments of Laboratory Medicine (A.P.L., T.R.F., B.T.C.) and Medicine (A.P.L., M.S., W.E.S.), University of Washington, Seattle; and the Department of Medicine, Indiana University School of Medicine, Indianapolis (P.A.C., L.J.W.).

Address reprint requests to Dr. Limaye at the Department of Laboratory Medicine, Box 357110, University of Washington Medical Center, 1959 NE Pacific St., Seattle, WA 98195-7110, or at limaye@u.washington.edu.

References

This article has been cited by other articles:

• Deepe, G. S. Jr., Gibbons, R. S. (2008). TNF-{alpha} Antagonism Generates a Population of Antigen-Specific CD4+CD25+ T Cells That Inhibit Protective Immunity in Murine Histoplasmosis. J. Immunol. 180: 1088-1097 [Abstract] [Full Text]  
• Martin-Davila, P., Fortun, J., Lopez-Velez, R., Norman, F., Montes de Oca, M., Zamarron, P., Gonzalez, M. I., Moreno, A., Pumarola, T., Garrido, G., Candela, A., Moreno, S. (2008). Transmission of Tropical and Geographically Restricted Infections during Solid-Organ Transplantation. Clin. Microbiol. Rev. 21: 60-96 [Abstract] [Full Text]  
• Allen, H. L., Deepe, G. S. Jr. (2006). B Cells and CD4-CD8- T Cells Are Key Regulators of the Severity of Reactivation Histoplasmosis. J. Immunol. 177: 1763-1771 [Abstract] [Full Text]  
• Buck, B. E., Malinin, T. I., Davis, J. H., Limaye, A. P., Sagar, M. (2001). Transmission of Histoplasmosis by Organ Transplantation. NEJM 344: 310-310 [Full Text]  
• (2000). Histoplasmosis Acquired from Transplantation. JWatch Infect. Diseases 2000: 9-9 [Full Text]