FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 343:1179-1182 October 19, 2000 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Lindahl, B. Related Article by Packard, C. J. PubMed Citation

The past decade has been characterized by growing interest in the idea that atherosclerosis is an inflammatory disease¹ and by the finding that serum levels of markers of inflammation can be used to predict the risk of cardiovascular events.² In this issue of the Journal are two reports — one by Lindahl et al.³ and one by Packard et al.⁴ — that advance our knowledge of these areas. Both studies made use of clinical trials to address whether levels of serum-based inflammatory markers were predictive of cardiovascular events.

Lindahl et al.³ addressed whether serum levels of cardiac troponin T, C-reactive . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Judge, M. S. (2008). Infection and Neuroarthropathy: The Utility of C-reactive Protein as a Screening Tool in the Charcot Foot. J. Am. Podiatr. Med. Assoc. 98: 1-6 [Abstract] [Full Text]  
• Evans, J., Collins, M., Jennings, C., van der Merwe, L., Soderstrom, I., Olsson, T., Levitt, N. S, Lambert, E. V, Goedecke, J. H (2007). The association of interleukin-18 genotype and serum levels with metabolic risk factors for cardiovascular disease. Eur J Endocrinol 157: 633-640 [Abstract] [Full Text]  
• Velasquez-Mieyer, P., Neira, C. P., Nieto, R., Cowan, P. A. (2007). Review: Obesity and cardiometabolic syndrome in children. Therapeutic Advances in Cardiovascular Disease 1: 61-81 [Abstract]  
• Rippe, J. M., Angelopoulos, T. J., Zukley, L. (2007). Lifestyle Medicine Strategies for Risk Factor Reduction, Prevention, and Treatment of Coronary Heart Disease: Part II. AMERICAN JOURNAL OF LIFESTYLE MEDICINE 1: 79-90 [Abstract]  
• Saura, M., Zaragoza, C., Bao, C., Herranz, B., Rodriguez-Puyol, M., Lowenstein, C. J. (2006). Stat3 Mediates Interelukin-6 Inhibition of Human Endothelial Nitric-oxide Synthase Expression. J. Biol. Chem. 281: 30057-30062 [Abstract] [Full Text]  
• Johnston, S. C., Zhang, H., Messina, L. M., Lawton, M. T., Dean, D. (2005). Chlamydia pneumoniae Burden in Carotid Arteries Is Associated With Upregulation of Plaque Interleukin-6 and Elevated C-Reactive Protein in Serum. Arterioscler. Thromb. Vasc. Bio. 25: 2648-2653 [Abstract] [Full Text]  
• Bonvini, R. F., Hendiri, T., Camenzind, E. (2005). Inflammatory response post-myocardial infarction and reperfusion: a new therapeutic target?. Eur Heart J Suppl 7: I27-I36 [Abstract] [Full Text]  
• Clearfield, M. B. (2005). C-Reactive Protein: A New Risk Assessment Tool for Cardiovascular Disease. JAOA: Journal of the American Osteopathic Association 105: 409-416 [Abstract] [Full Text]  
• Tietge, U. J. F., Pratico, D., Ding, T., Funk, C. D., Hildebrand, R. B., Van Berkel, T., Van Eck, M. (2005). Macrophage-specific expression of group IIA sPLA2 results in accelerated atherogenesis by increasing oxidative stress. J. Lipid Res. 46: 1604-1614 [Abstract] [Full Text]  
• Margolis, K. L., Manson, J. E., Greenland, P., Rodabough, R. J., Bray, P. F., Safford, M., Grimm, R. H. Jr, Howard, B. V., Assaf, A. R., Prentice, R., for the Women's Health Initiative Research Group, (2005). Leukocyte Count as a Predictor of Cardiovascular Events and Mortality in Postmenopausal Women: The Women's Health Initiative Observational Study. Arch Intern Med 165: 500-508 [Abstract] [Full Text]  
• Morrow, J. D. (2005). Quantification of Isoprostanes as Indices of Oxidant Stress and the Risk of Atherosclerosis in Humans. Arterioscler. Thromb. Vasc. Bio. 25: 279-286 [Abstract] [Full Text]  
• Sola, S., Mir, M. Q.S., Cheema, F. A., Khan-Merchant, N., Menon, R. G., Parthasarathy, S., Khan, B. V. (2005). Irbesartan and Lipoic Acid Improve Endothelial Function and Reduce Markers of Inflammation in the Metabolic Syndrome: Results of the Irbesartan and Lipoic Acid in Endothelial Dysfunction (ISLAND) Study. Circulation 111: 343-348 [Abstract] [Full Text]  
• Paschos, G. K., Yiannakouris, N., Rallidis, L. S., Davies, I., Griffin, B. A., Panagiotakos, D. B., Skopouli, F. N., Votteas, V., Zampelas, A. (2005). Apolipoprotein E Genotype in Dyslipidemic Patients and Response of Blood Lipids and Inflammatory Markers to Alpha-Linolenic Acid. ANGIOLOGY 56: 49-60 [Abstract]  
• Kerner, A., Avizohar, O., Sella, R., Bartha, P., Zinder, O., Markiewicz, W., Levy, Y., Brook, G. J., Aronson, D. (2005). Association Between Elevated Liver Enzymes and C-Reactive Protein: Possible Hepatic Contribution to Systemic Inflammation in the Metabolic Syndrome. Arterioscler. Thromb. Vasc. Bio. 25: 193-197 [Abstract] [Full Text]  
• Wisse, B. E. (2004). The Inflammatory Syndrome: The Role of Adipose Tissue Cytokines in Metabolic Disorders Linked to Obesity. J. Am. Soc. Nephrol. 15: 2792-2800 [Abstract] [Full Text]  
• Santos, S., Rooke, T. W, Bailey, K. R, McConnell, J. P, Kullo, I. J (2004). Relation of markers of inflammation (C-reactive protein, white blood cell count, and lipoprotein-associated phospholipase A2) to the ankle brachial index. Vasc Med 9: 171-176 [Abstract]  
• Khan, B. V., Sola, S., Lauten, W. B., Natarajan, R., Hooper, W. C., Menon, R. G., Lerakis, S., Helmy, T. (2004). Quinapril, an ACE Inhibitor, Reduces Markers of Oxidative Stress in the Metabolic Syndrome. Diabetes Care 27: 1712-1715 [Abstract] [Full Text]  
• Milani, R. V., Lavie, C. J., Mehra, M. R. (2004). Reduction in C-reactive protein through cardiac rehabilitation and exercise training. J Am Coll Cardiol 43: 1056-1061 [Abstract] [Full Text]  
• Kip, K. E., Marroquin, O. C., Kelley, D. E., Johnson, B. D., Kelsey, S. F., Shaw, L. J., Rogers, W. J., Reis, S. E. (2004). Clinical Importance of Obesity Versus the Metabolic Syndrome in Cardiovascular Risk in Women: A Report From the Women's Ischemia Syndrome Evaluation (WISE) Study. Circulation 109: 706-713 [Abstract] [Full Text]  
• Reilly, M. P., Rader, D. J. (2003). The Metabolic Syndrome: More Than the Sum of Its Parts?. Circulation 108: 1546-1551 [Full Text]  
• Dacey, L. J., DeSimone, J., Braxton, J. H., Leavitt, B. J., Lahey, S. J., Klemperer, J. D., Westbrook, B. M., Olmstead, E. M., O'Connor, G. T. (2003). Preoperative white blood cell count and mortality and morbidity after coronary artery bypass grafting. Ann. Thorac. Surg. 76: 760-764 [Abstract] [Full Text]  
• Gill, J. M. R., Caslake, M. J., McAllister, C., Tsofliou, F., Ferrell, W. R., Packard, C. J., Malkova, D. (2003). Effects of Short-Term Detraining on Postprandial Metabolism, Endothelial Function, and Inflammation in Endurance-Trained Men: Dissociation between Changes in Triglyceride Metabolism and Endothelial Function. J. Clin. Endocrinol. Metab. 88: 4328-4335 [Abstract] [Full Text]  
• Chapman, C. M.L., Beilby, J. P., Humphries, S. E., Palmer, L. J., Thompson, P. L., Hung, J. (2003). Association of an allelic variant of interleukin-6 with subclinical carotid atherosclerosis in an Australian community population. Eur Heart J 24: 1494-1499 [Abstract] [Full Text]  
• Jain, S. K., Kannan, K., Lim, G., Matthews-Greer, J., McVie, R., Bocchini, J. A. Jr (2003). Elevated Blood Interleukin-6 Levels in Hyperketonemic Type 1 Diabetic Patients and Secretion by Acetoacetate-Treated Cultured U937 Monocytes. Diabetes Care 26: 2139-2143 [Abstract] [Full Text]  
• Kitas, G. D., Erb, N. (2003). Tackling ischaemic heart disease in rheumatoid arthritis. Rheumatology (Oxford) 42: 607-613 [Full Text]  
• Jin, W., Sun, G.-S., Marchadier, D., Octtaviani, E., Glick, J. M., Rader, D. J. (2003). Endothelial Cells Secrete Triglyceride Lipase and Phospholipase Activities in Response to Cytokines as a Result of Endothelial Lipase. Circ. Res. 92: 644-650 [Abstract] [Full Text]  
• Morrow, J. D. (2003). Is Oxidant Stress a Connection Between Obesity and Atherosclerosis?. Arterioscler. Thromb. Vasc. Bio. 23: 368-370 [Full Text]  
• Isasi, C. R., Deckelbaum, R. J., Tracy, R. P., Starc, T. J., Berglund, L., Shea, S. (2003). Physical Fitness and C-Reactive Protein Level in Children and Young Adults: The Columbia University BioMarkers Study. Pediatrics 111: 332-338 [Abstract] [Full Text]  
• Schachinger, V., Zeiher, A. M. (2002). Atherogenesis--recent insights into basic mechanisms and their clinical impact. Nephrol Dial Transplant 17: 2055-2064 [Full Text]  
• Jain, S. K., Kannan, K., Lim, G., McVie, R., Bocchini, J. A. Jr. (2002). Hyperketonemia Increases Tumor Necrosis Factor-{alpha} Secretion in Cultured U937 Monocytes and Type 1 Diabetic Patients and Is Apparently Mediated by Oxidative Stress and cAMP Deficiency. Diabetes 51: 2287-2293 [Abstract] [Full Text]  
• Tietge, U. J.F., Maugeais, C., Lund-Katz, S., Grass, D., deBeer, F. C., Rader, D. J. (2002). Human Secretory Phospholipase A2 Mediates Decreased Plasma Levels of HDL Cholesterol and ApoA-I in Response to Inflammation in Human ApoA-I Transgenic Mice. Arterioscler. Thromb. Vasc. Bio. 22: 1213-1218 [Abstract] [Full Text]  
• Eckel, R. H., Barouch, W. W., Ershow, A. G. (2002). Report of the National Heart, Lung, and Blood Institute-National Institute of Diabetes and Digestive and Kidney Diseases Working Group on the Pathophysiology of Obesity-Associated Cardiovascular Disease. Circulation 105: 2923-2928 [Full Text]  
• Abou-Raya, S., Naeem, A., Kheir, H. A.-E., El Beltagy, S. (2002). Coronary Artery Disease and Periodontal Disease: Is There a Link?. ANGIOLOGY 53: 141-148 [Abstract]  
• Gorelick, P. B. (2002). Stroke Prevention Therapy Beyond Antithrombotics: Unifying Mechanisms in Ischemic Stroke Pathogenesis and Implications for Therapy: An Invited Review. Stroke 33: 862-875 [Abstract] [Full Text]  
• Johnston, S. C., Messina, L. M., Browner, W. S., Lawton, M. T., Morris, C., Dean, D. (2001). C-Reactive Protein Levels and Viable Chlamydia pneumoniae in Carotid Artery Atherosclerosis. Stroke 32: 2748-2752 [Abstract] [Full Text]  
• Lindmark, E., Diderholm, E., Wallentin, L., Siegbahn, A. (2001). Relationship Between Interleukin 6 and Mortality in Patients With Unstable Coronary Artery Disease: Effects of an Early Invasive or Noninvasive Strategy. JAMA 286: 2107-2113 [Abstract] [Full Text]  
• Blake, G. J., Dada, N., Fox, J. C., Manson, J. E., Ridker, P. M. (2001). A prospective evaluation of lipoprotein-associated phospholipase A2 levels and the risk of future cardiovascular events in women. J Am Coll Cardiol 38: 1302-1306 [Abstract] [Full Text]  
• Hegele, R. A., Ban, M. R., Young, T. K. (2001). Serum C-Reactive Protein in Canadian Inuit and Its Association with Genetic Variation on Chromosome 1q21. Clin. Chem. 47: 1707-1709 [Full Text]  
• Best, P.J.M., Gersh, B.J. (2001). Cell adhesion molecules and inflammation in acute coronary syndromes: markers and emerging risk factors. Eur Heart J 22: 1155-1159  
• Feldman, M., Jialal, I., Devaraj, S., Cryer, B. (2001). Effects of low-dose aspirin on serum C-reactive protein and thromboxane B2 concentrations: a placebo-controlled study using a highly sensitive C-reactive protein assay. J Am Coll Cardiol 37: 2036-2041 [Abstract] [Full Text]  
• Navab, M., Berliner, J. A., Subbanagounder, G., Hama, S., Lusis, A. J., Castellani, L. W., Reddy, S., Shih, D., Shi, W., Watson, A. D., Van Lenten, B. J., Vora, D., Fogelman, A. M. (2001). HDL and the Inflammatory Response Induced by LDL-Derived Oxidized Phospholipids. Arterioscler. Thromb. Vasc. Bio. 21: 481-488 [Abstract] [Full Text]