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Previous Volume 343:1263-1265 October 26, 2000 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The unprecedented spread of the human immunodeficiency virus (HIV) throughout the world has made the development of an effective AIDS vaccine one of the most urgent challenges facing biomedical science. The dissemination of the virus to more than 40 million people worldwide attests to the fact that immune resistance to HIV infection is rare. The virus is commonly transmitted through mucosal surfaces as a result of either sexual contact or oral exposure — for example, from breast-feeding. Neutralizing antibodies have a key role in immunity against many viruses, and their ability to confer protection at mucosal sites is of great . . . [Full Text of this Article]

References

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• Haicheur, N., Benchetrit, F., Amessou, M., Leclerc, C., Falguieres, T., Fayolle, C., Bismuth, E., Fridman, W. H., Johannes, L., Tartour, E. (2003). The B subunit of Shiga toxin coupled to full-size antigenic protein elicits humoral and cell-mediated immune responses associated with a Th1-dominant polarization. Int Immunol 15: 1161-1171 [Abstract] [Full Text]  
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• Hemming, V. G. (2001). Use of Intravenous Immunoglobulins for Prophylaxis or Treatment of Infectious Diseases. CVI 8: 859-863 [Full Text]