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Previous Volume 343:1336-1337 November 2, 2000 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Vichinsky et al. (June 22 issue)¹ showed that among 538 patients with sickle cell disease who were followed for four years, 16 percent of 670 episodes of the acute chest syndrome were caused by a pulmonary infarction. A total of 29 percent of the episodes were associated with infections, some occurring together with infarctions, so that a cause of the acute chest syndrome was found in only 38 percent of episodes. However, infections were diagnosed mostly on the basis of seroconversion and the detection of microorganisms or chlamydia antibody in cultures of nasopharyngeal aspirates and sputum. The . . . [Full Text of this Article]

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