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Previous Volume 343:108-117 July 13, 2000 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Lymphocytes and Lymphoid Tissue

The complexity of the cellular interactions that occur during acquired immune responses requires specialized microenvironments in which the relevant cells can collaborate efficiently. Because only a few lymphocytes are specific for a given antigen, T cells and B cells need to migrate throughout the body to increase the probability that they will encounter that particular antigen. In their travels, lymphocytes spend only about 30 minutes in the blood during each cycle around the body.⁵⁶

Immune responses to blood-borne antigens are usually initiated in the spleen, and responses to microorganisms in tissues are generated in local lymph nodes, but most pathogens . . . [Full Text of this Article]

Molecular Aspects of the Immune Response

Activation and Regulation of Lymphocytes

Effector Functions of T Cells

Immune Protection by Antibodies

Regulation of the Immune Response

Immunologic Technology

Source Information

From the Department of Immunology, the Windeyer Institute of Medical Sciences, University College London, London.

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