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Editorial
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Volume 343:136-138 July 13, 2000 Number 2
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Bioengineered Corneas — The Promise and the Challenge

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 by Tsai, R. J.-F.
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The promise of bioengineered replacements for diseased or damaged tissues has become a reality, notably for skin and cartilage. The article by Tsai et al. in this issue of the Journal 1 demonstrates the promise of a nascent form of technology that may provide a new tool for reconstructing damaged ocular surfaces that previously would have been unrepairable.

Conditions such as the Stevens–Johnson syndrome, cicatricial pemphigoid, and chemical burns, among others, can severely compromise ocular surfaces and cause catastrophic visual loss in otherwise healthy eyes; such problems afflict thousands of patients in North America every year.2 The global burden of blindness . . . [Full Text of this Article]

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