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Previous Volume 343:1573 November 23, 2000 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The medical mystery in the October 5 issue¹ involved a 19-year-old man, shown here in Figure 1, who had numerous dome-shaped elevations on the surface of the iris, or Lisch nodules. Lisch nodules are melanocytic hamartomas that are either yellow or brown. They are visible on inspection, pathognomonic of neurofibromatosis type 1, and do not cause symptoms. The incidence of Lisch nodules among patients with neurofibromatosis type 1 increases with age: at the age of 5 years only 22 percent have Lisch nodules, whereas at the age of 20 years 100 percent have them.² Therefore, older . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Wilkinson, E. P. (2001). The Evolution of the Physician's Role. JAMA 285: 2248-2248 [Full Text]