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A correction has been published: N Engl J Med 2001;344(7):536.

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Volume 343:1646-1649 November 30, 2000 Number 22
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In Whose Best Interest? Breaching the Academic–Industrial Wall

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Commentary
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 by Drazen, J. M.

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In 1799, Benjamin Waterhouse, one of the three full-time professors at Harvard Medical School, received a copy of Edward Jenner's Inquiry into the Causes and Effects of the Variolae Vaccinae. Armed with new knowledge of the efficacy of cowpox vaccination for the prevention of smallpox, Waterhouse proposed to test the vaccine in Boston and, if successful, to develop a monopoly under which he would inoculate New England children for a fee.1

After receiving the cowpox preparation from England, Waterhouse inoculated first his son Daniel, then six other members of his household. He next carried out a clinical study in which . . . [Full Text of this Article]

Conflict of Interest versus the Public Interest

The Evolving Ties between the University and Industry

Disadvantages of Breaching the Wall between Academia and Industry

Toward a Just and Prudent Balance

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