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Volume 343:1661-1662 November 30, 2000 Number 22

Asthma: Epidemiology, anti-inflammatory therapy and future trends

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(Respiratory Pharmacology and Pharmacotherapy.) Edited by Mark A. Giembycz and Brian J. O'Connor. 206 pp., illustrated. Boston, Birkhauser, 2000. $219. ISBN 3-7643-5858-0.

In the past two decades, enormous advances in molecular biology and immunology have revolutionized our understanding of disease processes. One disease that is better understood as a result of these advances is asthma. Concepts of the physiological processes of airway narrowing and bronchial hyperresponsiveness have been around for some time, but the integration of this knowledge with immunology has unraveled the mechanisms of these events and led to the understanding that asthma is an inflammatory disease. The delineation of the pathways to inflammation has made it possible to conceive of antiinflammatory mechanisms that explain the effectiveness of existing asthma therapies . . . [Full Text of this Article]




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