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Previous Volume 343:1815-1816 December 14, 2000 Number 24 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Morelon et al. (July 20 issue)¹ described three patients in whom interstitial pneumonitis was thought to be related to sirolimus therapy, because it occurred during therapy and resolved after sirolimus was discontinued and because other causes were absent.

To date, the Food and Drug Administration (FDA) has received reports of 34 cases of interstitial pneumonitis that were temporally associated with sirolimus therapy (including the 3 described by Morelon et al.). All but two case reports² were from clinical studies of sirolimus. Thirty-two patients were being treated with sirolimus after receiving kidney transplants, one after receiving a liver . . . [Full Text of this Article]

References

Related Letters:

Interstitial Pneumonitis Associated with Sirolimus Therapy in Renal-Transplant Recipients
Morelon E., Stern M., Kreis H.
Extract | Full Text  
N Engl J Med 2000; 343:225-226, Jul 20, 2000. Correspondence

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