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Previous Volume 343:1968-1969 December 28, 2000 Number 26 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In their study of plasma levels of factor VIII in relation to recurrent venous thrombosis, Kyrle et al. (Aug. 17 issue)¹ demonstrate the value of measuring factor VIII for predicting the risk of recurrence of thrombosis. However, some important issues need clarification.

The authors used C-reactive protein as a marker of acute inflammation to rule out transient elevations in factor VIII levels. No effort seems to have been made to rule out liver disease, which is a common cause of elevated factor VIII levels.² The levels of von Willebrand factor and the blood group are other determinants . . . [Full Text of this Article]

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