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Volume 343:302-303 July 27, 2000 Number 4
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Sedation and Analgesia for Procedures in Children

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 by Krauss, B.
To the Editor: We disagree with the approach to sedation and analgesia for children proposed by Krauss and Green in their review article (March 30 issue).1 Unfortunately, there is minimal outcomes-based research to guide these directives. The complication rate associated with sedation of children by nonanesthesiologists has been cited as 20 percent.2

First, treatment of opioid-induced respiratory depression consists of stimulation, ventilation, and oxygenation. Naloxone at a dose of 100 µg per kilogram of body weight has been cited as the dose for resuscitation from life-threatening opioid overdose but may precipitate the onset of pulmonary edema, hypertension, and seizures.3 Naloxone . . . [Full Text of this Article]

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