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Previous Volume 343:303-304 July 27, 2000 Number 4 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Before the diagnosis of cutaneous T-cell lymphoma was established in the case described by Poiesz et al. (March 30 issue),¹ several alternatives should have been considered. Patients with advanced human immunodeficiency virus (HIV) infection and low CD4+ T-cell counts may present with a massive cutaneous influx of CD8+ T lymphocytes. Although the findings in skin-biopsy specimens often mimic those in patients with cutaneous T-cell lymphoma, Southern blot and polymerase-chain-reaction (PCR) studies reveal a polyclonal pattern that suggests a reactive inflammatory process.^2,3 Furthermore, Bachelez et al. showed that the infiltrating CD8+ lymphocytes in such pseudolymphomas have specific major-histocompatibility-complex . . . [Full Text of this Article]

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