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Correspondence
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Volume 343:364-365 August 3, 2000 Number 5
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A Study in Rural Uganda of Heterosexual Transmission of Human Immunodeficiency Virus

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 by Quinn, T. C.
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To the Editor: Largely ignored in the report by Quinn et al. of their study of the heterosexual transmission of human immunodeficiency virus type 1 (HIV-1) in Uganda (March 30 issue)1 is the finding that of 137 uncircumcised men who were negative for HIV-1, 40 seroconverted, whereas 0 of 50 circumcised men seroconverted. This finding suggests that male circumcision is at least as protective against female-to-male transmission of HIV-1 as low viral load in the female partner. Yet the authors do not consider male circumcision among their list of possible strategies for the prevention of HIV-1 infection.

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