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Volume 343:369 August 3, 2000 Number 5
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Ulcerative Colitis in a Sigmoid Neovagina

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To the Editor: The cause of ulcerative colitis remains unknown. Direct exposure to alimentary antigens or intestinal bacterial flora may trigger the mucosal inflammation in persons who are predisposed to ulcerative colitis.1 We describe a case of ulcerative colitis involving the patient's sigmoid neovagina, in which the findings are evidence against either of these hypotheses.

A 60-year-old woman presented with a four-month history of abdominal pain in the left lower quadrant and bloody diarrhea. She had undergone vaginal reconstruction with a sigmoid-colon autotransplant at the age of 25 years because of congenital vaginal agenesis. She had never smoked and was . . . [Full Text of this Article]

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