Organ transplantation has evolved rapidly from the first earlysuccesses1 to the current widespread use of donated organs forthe treatment of end-stage kidney, heart, and liver failure.With limited supplies of organs and an increasing demand forthem, however, many patients who need transplants do not receivethem (Figure 1).2
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Figure 1. The Number of Patients on Waiting Lists for Transplants and the Number of Transplantations Performed in the United States in 1998.
Data are from the registry of the United Network for Organ Sharing. The pattern is similar for all major organ-transplantation programs.
Kidneys from Older Donors or Patients with Renal Disease
Other Organs from Older Donors
Expanding the Supply of Kidneys from Living Related and Unrelated Donors
One Liver for Two Patients
Lung Transplants
Conclusions
Source Information
From the Department of Immunology and Clinics of Organ Transplantation, Ospedali Riuniti di Bergamo, Mario Negri Institute for Pharmacological Research, Bergamo, Italy.
Address reprint requests to Dr. Remuzzi at the Mario Negri Institute for Pharmacological Research, Via Gavazzeni 11, 24125 Bergamo, Italy, or at gremuzzi@cyberg.it.
References
Related Letters:
Organs for Transplantation
Lopez-Navidad A., Caballero F., Bartlett S. T., Oldach D., Schimpff S. C., Selby R., Genyk Y., Jabbour N., Hilbrands L. B., Hordijk W., van der Vliet J. A., Remuzzi G., Gridelli B., Kahn J., Matas A.
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N Engl J Med 2000;
343:1730-1732, Dec 7, 2000.
Correspondence
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