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Original Article
Brief Report
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Volume 343:551-554 August 24, 2000 Number 8
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Treatment of Type II Gastric Carcinoid Tumors with Somatostatin Analogues
Paola Tomassetti, M.D., Marina Migliori, M.D., Gian Carlo Caletti, M.D., Pietro Fusaroli, M.D., Roberto Corinaldesi, M.D., and Lucio Gullo, M.D.

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Gastric carcinoid tumors are rare tumors that originate from gastric enterochromaffin-like cells in the oxyntic mucosa.1 There are three types of gastric carcinoid tumors: type I is associated with chronic atrophic gastritis, type II develops in patients with combined multiple endocrine neoplasia type 1 and the Zollinger–Ellison syndrome, and type III is sporadic.1 Although the pathogenesis of these tumors is not completely understood, hypergastrinemia has an important role in the development of types I and II.2 The multiple endocrine neoplasia type 1 gene locus may be involved in type II gastric carcinoid tumors.3,4

All three types are usually removed surgically . . . [Full Text of this Article]

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From the Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy.

Address reprint requests to Dr. Gullo at the Department of Internal Medicine and Gastroenterology, S. Orsola Hospital, Via Massarenti, 9, I-40138 Bologna, Italy.

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