Gastric carcinoid tumors are rare tumors that originate fromgastric enterochromaffin-like cells in the oxyntic mucosa.1There are three types of gastric carcinoid tumors: type I isassociated with chronic atrophic gastritis, type II developsin patients with combined multiple endocrine neoplasia type1 and the ZollingerEllison syndrome, and type III issporadic.1 Although the pathogenesis of these tumors is notcompletely understood, hypergastrinemia has an important rolein the development of types I and II.2 The multiple endocrineneoplasia type 1 gene locus may be involved in type II gastriccarcinoid tumors.3,4
From the Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy.
Address reprint requests to Dr. Gullo at the Department of Internal Medicine and Gastroenterology, S. Orsola Hospital, Via Massarenti, 9, I-40138 Bologna, Italy.
References
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Grozinsky-Glasberg, S., Kaltsas, G., Gur, C., Gal, E., Thomas, D., Fichman, S., Alexandraki, K., Barak, D., Glaser, B., Shimon, I., Gross, D. J
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Campana, D, Nori, F, Pezzilli, R, Piscitelli, L, Santini, D, Brocchi, E, Corinaldesi, R, Tomassetti, P
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Schott, M., Sagert, C., Willenberg, H. S., Schinner, S., Ramp, U., Varro, A., Raffel, A., Eisenberger, C., Zacharowski, K., Perren, A., Scherbaum, W. A.
(2007). Carcinogenic Hypergastrinemia: Signet-Ring Cell Carcinoma in a Patient with Multiple Endocrine Neoplasia Type 1 with Zollinger-Ellison's Syndrome. J. Clin. Endocrinol. Metab.
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Marx, S. J., Simonds, W. F.
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26: 615-661
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