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Figure 1. A 94-year-old woman presented with a five-day history of progressive abdominal pain, fever, and diarrhea. Approximately 4 weeks earlier, she had started a 10-day course of a second-generation cephalosporin for pneumonia. She had undergone a partial colectomy with colostomy for rectal cancer in 1986. On admission, she had a temperature of 38.3°C (101°F), diffuse abdominal tenderness without peritoneal signs, and leukocytosis (white-cell count of 15,000 per cubic millimeter). An abdominal computed tomographic scan (Panel A) showed diffuse thickening of the colonic wall (arrows) with pericolonic inflammation of the transverse and descending colon. Pseudomembranous colitis was diagnosed on . . . [Full Text of this Article] |