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Correspondence
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Volume 344:63-65 January 4, 2001 Number 1
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Prognostic Value of Left Ventricular Hypertrophy in Hypertrophic Cardiomyopathy

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To the Editor: On the basis of prospective data from a large cohort of patients with hypertrophic cardiomyopathy, Spirito et al. (June 15 issue)1 report that the magnitude of left ventricular hypertrophy is a significant predictor of sudden death. Furthermore, the use of implantable cardioverter–defibrillators is considered in patients with extreme left ventricular hypertrophy. Although the group data are impressive, we suggest that without a consideration of the underlying genotype, their predictive power is low, and their usefulness as a guide to the management of individual cases is minimal.

Sudden death in patients with hypertrophic cardiomyopathy has been attributed to . . . [Full Text of this Article]

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