FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 344:859-860 March 15, 2001 Number 11 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

To the Editor: We report on the phenomenon of intracardiac thrombosis with features of Löffler's syndrome observed in conjunction with interleukin-2 therapy.

Patient 1, a 26-year-old woman with stage IV Hodgkin's disease, began to receive a continuous infusion of recombinant human interleukin-2 (aldesleukin; Proleukin, Chiron) in an experimental outpatient protocol; the initial dose was 75,000 IU per kilogram of body weight per day and was increased weekly, as tolerated, to a maximum of 150,000 IU per kilogram per day. The patient had a corresponding increase in eosinophils in peripheral blood to a maximum of 11,400 cells per cubic millimeter.

On . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Belda, A, Borras-Blasco, J, Lopez-Montes, L, Rosique-Robles, D, Castera, E, Abad, J (2009). Foot ischaemia and toe skin necrosis associated with interleukin-2 infusion in an HIV-infected patient. Int J STD AIDS 20: 577-579 [Abstract] [Full Text]