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Previous Volume 344:940-941 March 22, 2001 Number 12 Next

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By Robert Pool. 304 pp., illustrated. New York, Oxford University Press, 2001. $27.50. ISBN 0-19-511853-7.

The mystery: people in industrialized societies are growing ever fatter, and attempts at sustainable weight loss often prove fruitless. The sleuths: scientists who, over the course of a century, arrive at some understanding of the complex interactions among genes, environment, and behavior that establish a person's body-weight "set point." The set point, moved upward by the successes of industrialization, appears recalcitrant to long-term change. But is it?

Robert Pool weaves a wonderful and balanced tale, linking the important 20th-century discoveries that led to the idea of the set point and our current understanding of the regulation of body weight. This . . . [Full Text of this Article]

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